Save on ONZETRA® Xsail® (sumatriptan nasal powder) Cost: Pay as Little as $0*

Prescribing Information

Patient Information

Save On ONZETRA

Pay as little as $0* + FREE Shipping^† for ONZETRA

Follow these 2 simple steps to SAVE on ONZETRA

Step 1

Transfer your Rx

Ask your doctor to transfer your prescription to Zeal Specialty Pharmacy. There are 2 ways to transfer your prescription.

Electronic Medical Records

Your doctor can select Zeal Specialty Pharmacy as the pharmacy of choice and submit the prescription.

100 Business Center Drive, Suite 300
Pittsburgh, PA 15205
NPI: 1093424905

Transfer by Fax

Your doctor can fax your prescription to Zeal Specialty Pharmacy at 1-877-329-9325

Step 2

Contact Zeal Specialty Pharmacy

A pharmacist from Zeal will contact you to obtain your insurance and address information.

Contact Zeal Specialty Pharmacy

To speak with Zeal Specialty Pharmacy directly, call 1-888-412-9325 or visit their website at www.zealsp.com/onzetra

Once verified, your ONZETRA Xsail prescription will be shipped to your home for FREE. Most prescriptions arrive within 5 business days.

*The price of ONZETRA may be as low as $0 per month with free shipping through the CurAccess Program. Available to patients who meet eligibility criteria with private or commercial prescription insurance coverage for ONZETRA.

^†Free shipping through the CurAccess Program is offered by a third-party partner.

Get Started with a Doctor

Ready to take control of your acute migraine pain? Make an appointment with a doctor online to learn if prescription ONZETRA is right for you.

Get Started with a Doctor

Ready to take control of your acute migraine pain? Make an appointment with a doctor online to learn if prescription ONZETRA is right for you.

IMPORTANT SAFETY INFORMATION

ONZETRA Xsail may cause serious side effects, including:

Heart attack and other heart problems, which may lead to death. Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw that is severe or does not go away
Changes in color or sensation in your fingers and toes (Raynaud’s syndrome)
Stomach and intestinal problems (gastrointestinal and colonic ischemic events)
Problems with blood circulation to your legs and feet (peripheral vascular ischemia)
Serious allergic reactions (symptoms include hives; tongue, mouth, lip, or throat swelling; problems breathing)
Medication overuse headaches. Some people who use ONZETRA Xsail too many times may have worse headaches. If your headaches get worse your doctor may decide to stop your treatment with ONZETRA Xsail
Serotonin syndrome, a rare but serious problem that can happen in people using ONZETRA Xsail, especially if ONZETRA Xsail is used with antidepressant medicines called SSRIs, SNRIs, or TCAs. Call your doctor right away if you have any of the following symptoms of serotonin syndrome: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; trouble walking; or nausea, vomiting, or diarrhea
Seizures. Seizures have happened in people taking sumatriptan who have never had seizures before

The most common side effects of ONZETRA Xsail are abnormal taste, discomfort of your nose or throat, runny nose, and stuffy nose. This is not a complete list of side effects. Tell your doctor about any side effect that bothers you or does not go away.

Who should not take ONZETRA Xsail?

Do not take ONZETRA Xsail or stop using ONZETRA Xsail if you:

Have heart problems or a history of heart problems
Have had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation
Have uncontrolled high blood pressure
Have hemiplegic migraines or basilar migraines. If you are not sure if you have these, ask your doctor
Have peripheral vascular disease (narrowing of blood vessels to the legs, arms, stomach, intestines, or kidneys)
Have taken other migraine medications in the last 24 hours, including other triptans, ergots, or ergot-type medications. Ask your doctor for a list of these medicines if you are not sure
Are taking a medicine called a monoamine oxidase inhibitor (MAOI). MAOIs cannot be taken within 14 days before or after taking ONZETRA Xsail
Have severe liver problems
Have an allergy to sumatriptan, the medicine in ONZETRA Xsail, or any of the components in ONZETRA Xsail

What should I tell my healthcare provider before taking ONZETRA Xsail?

Before you take ONZETRA Xsail, tell your doctor about all your medical conditions and all the medicines you take, including prescription medicines, especially antidepressants, and all over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while taking ONZETRA Xsail?

ONZETRA Xsail can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see the full Prescribing Information, including Patient Information and Instructions for Use for ONZETRA Xsail.

What is ONZETRA^® Xsail^®

What is ONZETRA^® Xsail^®

ONZETRA^® Xsail^® is a prescription medication approved for the acute treatment of migraine, with or without aura in adults. ONZETRA Xsail is used for people who have been told by a healthcare provider that they have migraine headaches. ONZETRA Xsail is not for the prevention of migraines or for other types of headaches, including cluster headache.

© 2025 Currax Pharmaceuticals LLC.
ONZ-0060-001 02/25

© 2025 Currax Pharmaceuticals LLC.
ONZ-0060-002 10/25

All rights reserved. ONZETRA and Xsail are registered trademarks of Currax Pharmaceuticals LLC. Breath Powered is a registered trademark of OptiNose AS.

© 2025 Currax Pharmaceuticals LLC. All rights reserved. ONZETRA and Xsail are registered trademarks of Currax Pharmaceuticals LLC. Breath Powered is a registered trademark of OptiNose AS.
ONZ-0060-001 02/25

© 2025 Currax Pharmaceuticals LLC. All rights reserved. ONZETRA and Xsail are registered trademarks of Currax Pharmaceuticals LLC. Breath Powered is a registered trademark of OptiNose AS.
ONZ-0060-002 10/25