OnTrack Support is a helpful program of support and information for ONZETRA® Xsail®.


Looking for Financial Assistance? Or even a way to get ONZETRA delivered to your home? As a member of OnTrack Support, you have access to it all.

Just call 1-844-ONZETRA (1-844-669-3872) to learn about everything below and more! 


    Co-Pay Savings Card

    With the help of an ONZETRA Co-Pay Savings Card, you can receive your first prescription with a $0 co-pay and pay no more than $25 per refill.*

    I want to request a card

    I have a Co-Pay Savings Card


    Questions about insurance coverage

    We can help verify your insurance coverage and any possible out-of-pocket costs for ONZETRA.


    Co-Pay Calculator

    Whether you have insurance or not, instantly find your monthly cost for ONZETRA

    Use the Co-Pay Calculator now


    Financial Assistance

    You may also be eligible for the Patient Assistance Program, which may cover the full cost of ONZETRA. It is designed to help those who have limited income and little or no prescription insurance.


    Free home delivery

    For your convenience, we can connect you to a pharmacy that will deliver ONZETRA right to your door.


    Helpful nurse hotline

    If you’d like to speak to a trained nurse about using ONZETRA, we have a special hotline just for that. Nurses are available to answer questions you have.

    Call 1-844-ONZETRA (1-844-669-3872) Monday–Friday from 8:00 am – 7:00 pm EST.

    *Restrictions apply. Must have private insurance. Those eligible for Medicare, Medicaid, or any other government healthcare program are not eligible for this program. Card must be activated to receive $0 co-pay. Maximum benefit of $100 per prescription regardless of the co-pay amount.


It’s all about staying connected with up-to-date ONZETRA news and info. Once you start treatment, you'll continue to get the resources you need, including:

  • Exciting ONZETRA news
  • Helpful tips and advice

Important Safety Information

ONZETRA Xsail may cause serious side effects, including heart attack and other heart problems, which may lead to death. Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw that is severe or does not go away. Click here for more information

Important Safety Information

What is ONZETRA® Xsail® (sumatriptan nasal powder) used for?
ONZETRA Xsail is a prescription medication approved for the acute treatment of migraine, with or without aura in adults. ONZETRA Xsail is used for people who have been told by a healthcare provider that they have migraine headaches. ONZETRA Xsail is not for the prevention of migraines or for other types of headaches, including cluster headache.

What important information should I know about ONZETRA Xsail?
ONZETRA Xsail may cause serious side effects, including:

  • Heart attack and other heart problems, which may lead to death. Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw that is severe or does not go away
  • Changes in color or sensation in your fingers and toes (Raynaud’s syndrome)
  • Stomach and intestinal problems (gastrointestinal and colonic ischemic events)
  • Problems with blood circulation to your legs and feet (peripheral vascular ischemia)
  • Serious allergic reactions (symptoms include hives; tongue, mouth, lip, or throat swelling; problems breathing)
  • Medication overuse headaches. Some people who use ONZETRA Xsail too many times may have worse headaches. If your headaches get worse your doctor may decide to stop your treatment with ONZETRA Xsail
  • Serotonin syndrome, a rare but serious problem that can happen in people using ONZETRA Xsail, especially if ONZETRA Xsail is used with antidepressant medicines called SSRIs, SNRIs, or TCAs. Call your doctor right away if you have any of the following symptoms of serotonin syndrome: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; trouble walking; or nausea, vomiting, or diarrhea
  • Seizures. Seizures have happened in people taking sumatriptan who have never had seizures before

The most common side effects of ONZETRA Xsail are abnormal taste, discomfort of your nose or throat, runny nose, and stuffy nose. This is not a complete list of side effects. Tell your doctor about any side effect that bothers you or does not go away.

Who should not take ONZETRA Xsail?
Do not take ONZETRA Xsail or stop using ONZETRA Xsail if you:

  • Have heart problems or a history of heart problems
  • Have had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation
  • Have uncontrolled high blood pressure
  • Have hemiplegic migraines or basilar migraines. If you are not sure if you have these, ask your doctor
  • Have peripheral vascular disease (narrowing of blood vessels to the legs, arms, stomach, intestines, or kidneys)
  • Have taken other migraine medications in the last 24 hours, including other triptans, ergots, or ergot-type medications. Ask your doctor for a list of these medicines if you are not sure
  • Are taking a medicine called a monoamine oxidase inhibitor (MAOI). MAOIs cannot be taken within 14 days before or after taking ONZETRA Xsail
  • Have severe liver problems
  • Have an allergy to sumatriptan, the medicine in ONZETRA Xsail, or any of the components in ONZETRA Xsail

What should I tell my healthcare provider before taking ONZETRA Xsail?
Before you take ONZETRA Xsail, tell your doctor about all your medical conditions and all the medicines you take, including prescription medicines, especially antidepressants, and all over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while taking ONZETRA Xsail?
ONZETRA Xsail can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 800-FDA-1088.

For additional Important Safety Information about ONZETRA Xsail, please see the full Prescribing Information, including Patient Information and Instructions for Use.