Avanir Pharmaceuticals, Inc. ("Avanir") ordinarily does not prohibit links to this website, provided that any such link does not improperly connote an endorsement by or affiliation with Avanir, or otherwise adversely impact Avanir, and pursuant to the terms below.

If you are interested in linking to this website or any other Avanir-owned Web Sites, please notify Avanir Pharmaceuticals by sending an e-mail to webmaster@avanir.com. Include your name, your organization name, contact information (such as a phone number and/or e-mail address), as well as the URL of your site and a list of any URLs from which you intend to link to this site.

By linking to any page on the Avanir website, you hereby agree to be bound by the terms and conditions as set forth below.

Links may be text-based using the words: "onzetra.com," "Avanir," "Avanir Pharmaceuticals, Inc.," or "Avanir.com" (the "Avanir Marks"). You may not use any Avanir logo as a link. By linking, you acknowledge and agree that, other than as set forth herein, all rights to the Avanir Marks, other Avanir marks, the content appearing on the Avanir Website and the design of the Avanir Website belong to Avanir Pharmaceuticals, Inc. Nothing contained herein shall be construed as conferring by implication, estoppel, or otherwise any license or right under any patent, trademark, or copyright owned by Avanir Pharmaceuticals, Inc.

You may not create frames around any of the pages of the Avanir website or use other techniques that alter in any way the visual presentation or appearance of any of the Avanir website.

You must not misrepresent your relationship with any Avanir product or Avanir Pharmaceuticals, Inc. (or any Avanir-owned business entity, Avanir subsidiary, or Avanir-affiliated business entity) or present false or misleading impressions about any Avanir product or Avanir Pharmaceuticals, Inc. (or any Avanir-owned business entity, Avanir subsidiary, or Avanir-affiliated business entity). No links to any Avanir website may be used in a manner that implies or suggests that Avanir approves or endorses you, your website, or your goods and services (in all cases, except as Avanir may have agreed separately with you in writing).

Avanir has no responsibility or liability for any content appearing on your website. You agree to indemnify and defend Avanir against all claims arising out of or based upon your Website.

No link(s) may appear on any page on your website or within any context containing content or materials that may be interpreted as libelous; obscene or criminal; or which infringes, otherwise violates, or advocates the infringement or other violation of, any third-party rights.

Avanir may at any time, in its sole discretion, without cause, terminate your right to link to any Web pages of any Avanir Website. In such event, upon request, you agree to immediately remove all links to any Avanir website and to cease using the Avanir Marks.

Avanir reserves the right to change this linking policy at any time without notice, and such changes will be deemed effective upon posting. Changes will be posted on this page.

This website Linking Policy is effective as of May 9, 2016.  

Important Safety Information

ONZETRA Xsail may cause serious side effects, including heart attack and other heart problems, which may lead to death. Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw that is severe or does not go away. Click here for more information

Important Safety Information

What is ONZETRA® Xsail® (sumatriptan nasal powder) used for?
ONZETRA Xsail is a prescription medication approved for the acute treatment of migraine, with or without aura in adults. ONZETRA Xsail is used for people who have been told by a healthcare provider that they have migraine headaches. ONZETRA Xsail is not for the prevention of migraines or for other types of headaches, including cluster headache.

What important information should I know about ONZETRA Xsail?
ONZETRA Xsail may cause serious side effects, including:

  • Heart attack and other heart problems, which may lead to death. Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw that is severe or does not go away
  • Changes in color or sensation in your fingers and toes (Raynaud’s syndrome)
  • Stomach and intestinal problems (gastrointestinal and colonic ischemic events)
  • Problems with blood circulation to your legs and feet (peripheral vascular ischemia)
  • Serious allergic reactions (symptoms include hives; tongue, mouth, lip, or throat swelling; problems breathing)
  • Medication overuse headaches. Some people who use ONZETRA Xsail too many times may have worse headaches. If your headaches get worse your doctor may decide to stop your treatment with ONZETRA Xsail
  • Serotonin syndrome, a rare but serious problem that can happen in people using ONZETRA Xsail, especially if ONZETRA Xsail is used with antidepressant medicines called SSRIs, SNRIs, or TCAs. Call your doctor right away if you have any of the following symptoms of serotonin syndrome: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; trouble walking; or nausea, vomiting, or diarrhea
  • Seizures. Seizures have happened in people taking sumatriptan who have never had seizures before

The most common side effects of ONZETRA Xsail are abnormal taste, discomfort of your nose or throat, runny nose, and stuffy nose. This is not a complete list of side effects. Tell your doctor about any side effect that bothers you or does not go away.

Who should not take ONZETRA Xsail?
Do not take ONZETRA Xsail or stop using ONZETRA Xsail if you:

  • Have heart problems or a history of heart problems
  • Have had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation
  • Have uncontrolled high blood pressure
  • Have hemiplegic migraines or basilar migraines. If you are not sure if you have these, ask your doctor
  • Have peripheral vascular disease (narrowing of blood vessels to the legs, arms, stomach, intestines, or kidneys)
  • Have taken other migraine medications in the last 24 hours, including other triptans, ergots, or ergot-type medications. Ask your doctor for a list of these medicines if you are not sure
  • Are taking a medicine called a monoamine oxidase inhibitor (MAOI). MAOIs cannot be taken within 14 days before or after taking ONZETRA Xsail
  • Have severe liver problems
  • Have an allergy to sumatriptan, the medicine in ONZETRA Xsail, or any of the components in ONZETRA Xsail

What should I tell my healthcare provider before taking ONZETRA Xsail?
Before you take ONZETRA Xsail, tell your doctor about all your medical conditions and all the medicines you take, including prescription medicines, especially antidepressants, and all over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while taking ONZETRA Xsail?
ONZETRA Xsail can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 800-FDA-1088.

For additional Important Safety Information about ONZETRA Xsail, please see the full Prescribing Information, including Patient Information and Instructions for Use.