Migraine Relief in as little as 30 Minutes*

Fast & Effective Migraine Relief

*A large proportion of migraine sufferers had significant pain relief  with ONZETRA (42%) vs placebo (27%)

Blow Migraine Pain Away With ONZETRA Xsail: Breath Powered® Delivery*

The unique device delivers sumatriptan in the form of a powder directly to the back of the nose.

Sumatriptan, the active ingredient in ONZETRA, is the most widely prescribed migraine medication and has been used to treat acute migraines for nearly 30 years. 

*Twice as many people taking ONZETRA were pain-free at 2 hours compared to people taking a placebo (34% vs 17% respectively).

Why it Works

The back of your nose is full of absorbent tissue and blood vessels, which allows the powder medication to be absorbed quickly.

Breath Powered delivery also limits medication from dripping into your throat or reaching your stomach or lungs.

Onzetra Xsail application device for fast relief

Blow Migraine Pain Away With ONZETRA Xsail: Breath Powered® Delivery

The unique device delivers sumatriptan in the form of a powder directly to the back of the nose.

Sumatriptan, the active ingredient in ONZETRA, is the most widely prescribed migraine medication and has been used to treat acute migraines for nearly 30 years.

*Twice as many people taking ONZETRA were pain-free at 2 hours compared to people taking a placebo (34% vs 17% respectively).

Onzetra Xsail application device for fast relief
Why it Works 

The back of your nose is full of absorbent tissue and blood vessels, which allows the powder medication to be absorbed quickly.

Breath Powered delivery also limits medication from dripping into your throat or reaching your stomach or lungs.

Do You Have Questions?

We have answers to help you better understand how ONZETRA provides relief from migraine pain.

Get Started with a Doctor

Ready to take control of your acute migraine pain? Make an appointment with a doctor online to learn if prescription ONZETRA is right for you. 

Relief is just a few clicks away

Talk to a doctor online and find out if ONZETRA is right for you

If you have more questions, please visit our FAQs page
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1. Answer a few quick questions about your medical history

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2. In less than 24 hours, speak to a healthcare professional in your state to see if ONZETRA is right for you

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3. Get FREE shipping and have ONZETRA delivered straight to your door

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